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Percocet, containing oxycodone and acetaminophen, is a prescription opioid used to treat moderate to severe pain. It works by binding to opioid receptors in the brain and spinal cord, altering the perception of pain, while acetaminophen enhances overall pain relief.Percocet is an opioid analgesic. Oxycodone binds to opioid receptors, decreasing the perception of pain, while acetaminophen supports pain relief and reduces inflammation. Percocet is intended for short-term use under strict medical supervision, as long-term use increases risks of dependence and serious side effects.